PT-141
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PT-141 (Bremelanotide)
In short
PT-141 (Bremelanotide) is a Libidopeptide; its molecular target in research is Libido · erectie. Offered strictly for laboratory research, with a certificate of analysis (CoA) per batch on request.
For laboratory and research use only. Not for human or animal consumption, diagnostics or therapeutic use.
TogoPeptide Research Team · Research & quality
Research-only. Fact-checked, no medical or dosing claims. Every batch with a CoA. CoA
PT-141 (Bremelanotide) is a synthetic peptide analog derived from the melanocortin family. In preclinical research, the compound serves as a model substance for studying melanocortin receptor pharmacology, with particular attention to MC4R-related signal transduction in cell and animal models.
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Studied for libido and hormone balance
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| Type | Libidopeptide |
|---|---|
| Form | Freeze-dried powder |
| Purity | As stated on the batch CoA |
| Certificate | Per batch, on request |
| Use | Research only |
What is the molecular class of PT-141?
PT-141 belongs to the class of cyclic heptapeptides and is structurally derived from alpha-MSH (alpha-melanocyte-stimulating hormone), the endogenous melanocortin peptide that served as the template for several synthetic analogs. Like Melanotan II (MT-2), the compound shares a common core structure within the melanocortin family but differs through a distinct amino acid pattern. Researchers use this structural relationship to design comparative studies between different melanocortin analogs and their receptor subtype binding profiles.
Why does MC4R selectivity matter?
The melanocortin receptor family comprises five subtypes (MC1R through MC5R), each linked to different physiological processes in model organisms. MC1R is primarily associated with pigmentation processes, while MC4R is linked in preclinical literature to other neuroendocrine signaling pathways. PT-141 is described in research as a compound with a binding profile directed toward MC4R and MC3R alongside MC1R, making it a useful tool for distinguishing receptor-specific signal transduction from MC1R-driven processes. This differentiation is a recurring theme in comparative receptor pharmacology.
What research areas study PT-141?
In the scientific literature, PT-141 appears across several research lines: in vitro receptor binding assays, studies of intracellular signal transduction cascades (including cAMP-mediated pathways), and neuroendocrine model systems mapping melanocortin signaling. The compound is also used in structure-activity relationship (SAR) research, where small changes in peptide sequence are linked to changes in receptor affinity. This type of research contributes to a better fundamental understanding of melanocortin-mediated cell signaling in laboratory settings.
Why does a CoA matter for PT-141?
A Certificate of Analysis (CoA) confirms identity, purity, and molecular weight of a research peptide using techniques such as HPLC and mass spectrometry. Batch consistency is essential for reproducible preclinical results, since variation in purity can affect binding assays and signal transduction measurements. Research institutions therefore routinely consult a supplier's CoA before including a peptide in an experimental design.
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Frequently asked questions
Is PT-141 the same as Melanotan II?
No. Both are synthetic melanocortin analogs structurally related to alpha-MSH, but they differ in amino acid sequence and receptor binding profile. In comparative research they are often studied alongside each other to map receptor selectivity.
Is PT-141 being studied for use in humans?
This material concerns exclusively preclinical, receptor pharmacology research in cell and animal models. No human applications, dosing, or usage claims are described here.
Why is receptor selectivity a central theme in this research?
Because the melanocortin receptor subtypes activate different signaling pathways, distinguishing MC4R- from MC1R-mediated effects helps researchers isolate and study specific physiological processes in model systems.
How much does PT-141 (Bremelanotide) cost?
At TogoPeptide, PT-141 (Bremelanotide) is available from €34.99 per vial. The price depends on the amount (mg per vial). Every batch comes with a certificate of analysis (CoA), available on request.